Lawrence Paul Yuxweluptun's strategy is to document and promote change in contemporary Indigenous history through large scale acrylic on canvas pieces with brush and/or a palette knife. He makes use of vivid colours and his work presents a positive aesthetic impression as well as expression of content that is often bi-cultural. In his work Yuxweluptun uses Coast Salish cosmology, Northwest Coast formal design elements, and the Western landscape tradition. His painted works explore political, environmental, and cultural issues. His personal and socio-political experiences enhance this practice of documentation. Yuxweluptun's work has been included in numerous international group and solo exhibitions, such as INDIGENA: Contemporary Native Perspectives in 1992. He was the recipient of the Vancouver Institute for the Visual Arts (VIVA) award in 1998.
Much of the content of his work is derived from contemporary Native social and political issues. His father at one time was President of the North American Indian Brotherhood and his mother was Executive Director of the Indian Homemakers Association.